Information Package / Course Catalogue
Applied Molecular Genetics
Course Code: TBY208
Course Type: Area Elective
Couse Group: First Cycle (Bachelor's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 0
Credit: 3
Lab: 1
ECTS: 4
Objectives of the Course

This course aims to provide students with fundamental knowledge of molecular genetics, including the structure and organization of genetic material, gene expression, mutation mechanisms, and genome analysis. It also aims to develop practical skills in essential molecular genetics laboratory techniques, such as DNA isolation, DNA quality and quantity assessment, PCR, electrophoresis, RFLP, and microarray analysis, enabling students to analyze and interpret molecular genetic data.

Course Content

This course covers the structure of the nucleus and genetic material, chromatin and chromosome organization, the central dogma, mutations and mutation analysis methods, gene and genome structure, genomics, proteomics, the cell cycle, programmed cell death, immunogenetics, stem cell biology, gene–environment interactions, pharmacogenomics, and cellular aging. The laboratory component includes the principles and practical applications of DNA isolation, DNA quality and quantity assessment, PCR optimization, agarose gel electrophoresis, capillary electrophoresis, RFLP, and microarray techniques.

Name of Lecturer(s)
Learning Outcomes
1.Explain the organization of genetic material, chromatin and chromosome structure, the central dogma, gene and genome organization, and the molecular mechanisms of mutations.
2.Perform fundamental molecular genetics laboratory techniques, including DNA isolation, DNA quality and quantity assessment, PCR optimization, agarose gel electrophoresis, and capillary electrophoresis, and evaluate the obtained results.
3.Explain the principles of molecular analysis techniques, including mutation analysis methods, RFLP, and microarray technologies, and select and interpret appropriate methods for research and diagnostic applications.
4.Analyze and relate contemporary applications of molecular genetics, including genomics, proteomics, immunogenetics, pharmacogenomics, stem cell biology, the cell cycle, programmed cell death, and gene–environment interactions.
5.Interpret molecular genetic data using a scientific approach, report laboratory findings, and draw evidence-based conclusions for solving genetics-related problems.
Recommended or Required Reading
1.Moleküler Genetiğin Esasları. H. Ümit Lüleyap, Adana Nobel Kitabevi
2.GENETİCS (A Molecular Approach), Peter J. RUSSELL
Weekly Detailed Course Contents
Week 1 - Theoretical
Nucleus and Genetic Material
Week 1 - Laboratory
DNA isolation
Week 2 - Theoretical
Chromatin structure and Chromosomes
Week 2 - Laboratory
DNA isolation
Week 3 - Theoretical
Central Dogma
Week 3 - Laboratory
DNA Quality and Quantity determination
Week 4 - Theoretical
Mutation Types, Mutation Occurrence Mechanisms
Week 4 - Laboratory
DNA Quality and Quantity determination
Week 5 - Theoretical
Mutation Analysis Methods
Week 5 - Laboratory
PCR Optimisation
Week 6 - Theoretical
Gene and Genome Structure and Analysis
Week 6 - Laboratory
PCR Optimisation
Week 7 - Theoretical
Genomics and Proteomics
Week 7 - Laboratory
Agarose Gel Electrophoresis
Week 8 - Theoretical
Cell Cycle and Control
Week 8 - Laboratory
Agarose Gel Electrophoresis
Week 9 - Theoretical
Programmed Cell Death
Week 9 - Laboratory
RFLP
Week 10 - Theoretical
Immunogenetics and Immunity
Week 10 - Laboratory
RFLP
Week 11 - Theoretical
Stem cells
Week 11 - Laboratory
Capillary Electrophoresis
Week 12 - Theoretical
Gene and Environment Interaction
Week 12 - Laboratory
Capillary Electrophoresis
Week 13 - Theoretical
Pharmacogenomics
Week 13 - Laboratory
Microarray
Week 14 - Theoretical
Cell aging and genetics
Week 14 - Laboratory
Microarray
Assessment Methods and Criteria
Type of AssessmentCountPercent
Quiz1%5
Practice Examination1%5
Midterm Examination1%30
Final Examination1%60
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory142256
Lecture - Practice141128
Practice Examination1213
Quiz1213
Midterm Examination1415
Final Examination1415
TOTAL WORKLOAD (hours)100
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
OÇ-1
5
4
4
5
5
4
2
5
4
3
5
OÇ-2
4
4
5
4
3
5
3
4
3
2
3
OÇ-3
3
5
3
3
4
4
3
3
5
3
3
OÇ-4
5
3
4
4
4
3
2
5
4
2
2
OÇ-5
4
5
5
4
5
4
5
4
4
4
4
Adnan Menderes University - Information Package / Course Catalogue
2026