
| Course Code | : TBY208 |
| Course Type | : Area Elective |
| Couse Group | : First Cycle (Bachelor's Degree) |
| Education Language | : Turkish |
| Work Placement | : N/A |
| Theory | : 2 |
| Prt. | : 0 |
| Credit | : 3 |
| Lab | : 1 |
| ECTS | : 4 |
This course aims to provide students with fundamental knowledge of molecular genetics, including the structure and organization of genetic material, gene expression, mutation mechanisms, and genome analysis. It also aims to develop practical skills in essential molecular genetics laboratory techniques, such as DNA isolation, DNA quality and quantity assessment, PCR, electrophoresis, RFLP, and microarray analysis, enabling students to analyze and interpret molecular genetic data.
This course covers the structure of the nucleus and genetic material, chromatin and chromosome organization, the central dogma, mutations and mutation analysis methods, gene and genome structure, genomics, proteomics, the cell cycle, programmed cell death, immunogenetics, stem cell biology, gene–environment interactions, pharmacogenomics, and cellular aging. The laboratory component includes the principles and practical applications of DNA isolation, DNA quality and quantity assessment, PCR optimization, agarose gel electrophoresis, capillary electrophoresis, RFLP, and microarray techniques.
| 1. | Explain the organization of genetic material, chromatin and chromosome structure, the central dogma, gene and genome organization, and the molecular mechanisms of mutations. |
| 2. | Perform fundamental molecular genetics laboratory techniques, including DNA isolation, DNA quality and quantity assessment, PCR optimization, agarose gel electrophoresis, and capillary electrophoresis, and evaluate the obtained results. |
| 3. | Explain the principles of molecular analysis techniques, including mutation analysis methods, RFLP, and microarray technologies, and select and interpret appropriate methods for research and diagnostic applications. |
| 4. | Analyze and relate contemporary applications of molecular genetics, including genomics, proteomics, immunogenetics, pharmacogenomics, stem cell biology, the cell cycle, programmed cell death, and gene–environment interactions. |
| 5. | Interpret molecular genetic data using a scientific approach, report laboratory findings, and draw evidence-based conclusions for solving genetics-related problems. |
| 1. | Moleküler Genetiğin Esasları. H. Ümit Lüleyap, Adana Nobel Kitabevi |
| 2. | GENETİCS (A Molecular Approach), Peter J. RUSSELL |
| Type of Assessment | Count | Percent |
|---|---|---|
| Quiz | 1 | %5 |
| Practice Examination | 1 | %5 |
| Midterm Examination | 1 | %30 |
| Final Examination | 1 | %60 |
| Activities | Count | Preparation | Time | Total Work Load (hours) |
|---|---|---|---|---|
| Lecture - Theory | 14 | 2 | 2 | 56 |
| Lecture - Practice | 14 | 1 | 1 | 28 |
| Practice Examination | 1 | 2 | 1 | 3 |
| Quiz | 1 | 2 | 1 | 3 |
| Midterm Examination | 1 | 4 | 1 | 5 |
| Final Examination | 1 | 4 | 1 | 5 |
| TOTAL WORKLOAD (hours) | 100 | |||
PÇ-1 | PÇ-2 | PÇ-3 | PÇ-4 | PÇ-5 | PÇ-6 | PÇ-7 | PÇ-8 | PÇ-9 | PÇ-10 | PÇ-11 | |
OÇ-1 | 5 | 4 | 4 | 5 | 5 | 4 | 2 | 5 | 4 | 3 | 5 |
OÇ-2 | 4 | 4 | 5 | 4 | 3 | 5 | 3 | 4 | 3 | 2 | 3 |
OÇ-3 | 3 | 5 | 3 | 3 | 4 | 4 | 3 | 3 | 5 | 3 | 3 |
OÇ-4 | 5 | 3 | 4 | 4 | 4 | 3 | 2 | 5 | 4 | 2 | 2 |
OÇ-5 | 4 | 5 | 5 | 4 | 5 | 4 | 5 | 4 | 4 | 4 | 4 |