Information Package / Course Catalogue
Clinical Biochemistry
Course Code: TIP027
Course Type: Required
Couse Group: First Cycle (Bachelor's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 0
Credit: 2
Lab: 0
ECTS: 2
Objectives of the Course

To understand the causes of dentistry-related diseases by learning metabolism, and to be able to apply the steps of disease prevention and treatment.

Course Content

his course aims to teach the fundamental processes of metabolism and to provide an understanding of the causes, prevention, and treatment approaches of dentistry-related diseases based on biochemical principles.

Name of Lecturer(s)
Assoc. Prof. Mustafa YILMAZ
Lec. Ayça TUZCU
Lec. Burçin İrem ABAS
Prof. Aslıhan BÜYÜKÖZTÜRK
Learning Outcomes
1.Students will be able to explain the structure, metabolism, and regulation of carbohydrates, including glycolysis, TCA cycle, and related pathways.
2.Students will demonstrate understanding of lipid biochemistry, including digestion, absorption, synthesis, oxidation, and regulatory mechanisms.
3.Students will describe protein digestion processes, amino acid biosynthesis and degradation, as well as the urea cycle and related metabolic pathways.
4.Students will analyze the biochemical basis of blood coagulation, plasma proteins, connective tissue components, and extracellular matrix functions
5.Students will understand hormone classification, signal transduction mechanisms, and the metabolic regulation of calcium, phosphorus, magnesium, and bone remodeling markers.
Recommended or Required Reading
1.Harper's Illustrated Bıochemıstry 32. Baskı
2.Lippincott’s Illustrated Reviews:Biochemistry Fifth Edition
3.Lehninger Principles Of Biochemistry by David L.-Nelson Michael M.Cox
4.Marks Clinical Fundamentals of Medical Biochemistry 2nd Edition
Weekly Detailed Course Contents
Week 1 - Theoretical
Structure of Carbohydrates (Spring Semester)
Week 2 - Theoretical
Digestion, Absorption, and Utilization of Carbohydrates
Week 3 - Theoretical
Regulation of Glycolysis and the TCA Cycle
Week 4 - Theoretical
Oxidative Phosphorylation and Its Regulation
Week 5 - Theoretical
Glycogenesis, Glycogenolysis, Gluconeogenesis, and Their Regulation
Week 6 - Theoretical
Pentose Phosphate Pathway and Its Regulation, Metabolism of Fructose and Galactose
Week 7 - Practice
Carbohydrates and Antioxidants (Practical Application)
Week 8 - Theoretical
General Characteristics of Lipids
Week 9 - Theoretical
Digestion, Absorption, and Utilization of Lipids
Week 10 - Theoretical
Structure and Function of Membranes
Week 11 - Theoretical
Synthesis, Oxidation, and Regulation of Cholesterol and Fatty Acids
Week 12 - Theoretical
Synthesis and Degradation of Ketone Bodies, Eicosanoids and Their Synthesis
Week 13 - Theoretical
Oxidative Stress and Antioxidants
Week 14 - Theoretical
Oxidative Stress and Antioxidants
Week 15 - Theoretical
Protein Digestion and Proteases
Week 16 - Theoretical
Biosynthesis and Degradation of Amino Acids
Week 17 - Theoretical
Urea Cycle
Week 18 - Theoretical
Synthesis and Degradation of Porphyrins, Amino Acid-Derived Compounds
Week 19 - Practice
Plasma Proteins
Week 20 - Theoretical
Biochemistry of Bleeding and Coagulation
Week 21 - Theoretical
Connective Tissue and Components of the Extracellular Matrix
Week 22 - Theoretical
Classification and General Characteristics of Hormones
Week 23 - Theoretical
Signal Transduction Mechanisms
Week 24 - Theoretical
Stress and Hormones
Week 25 - Theoretical
Metabolism of Calcitonin, Parathyroid Hormone, and Vitamin D
Week 26 - Theoretical
Metabolism of Calcium, Phosphorus, and Magnesium
Week 27 - Theoretical
Markers of Bone Formation and Resorption
Week 28 - Theoretical
Markers of Bone Formation and Resorption
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination2%40
Final Examination1%60
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory500150
Midterm Examination1011
Final Examination1011
TOTAL WORKLOAD (hours)52
Contribution of Learning Outcomes to Programme Outcomes