Information Package / Course Catalogue
| Course Code | : TIP027 |
| Course Type | : Required |
| Couse Group | : First Cycle (Bachelor's Degree) |
| Education Language | : Turkish |
| Work Placement | : N/A |
| Theory | : 2 |
| Prt. | : 0 |
| Credit | : 2 |
| Lab | : 0 |
| ECTS | : 3 |
The objective of this course is to provide students with a comprehensive understanding of core macromolecular (carbohydrate, lipid, protein) metabolic pathways and their integrated regulatory mechanisms at cellular and systemic levels. Additionally, it aims to cultivate an advanced academic capacity to analyze cellular signal transduction networks, membrane dynamics, biochemical homeostasis (mineral, bone, and coagulation matrices), and the pathophysiology of oxidative stress, thereby establishing a rigorous foundation for clinical correlations and evidence-based medical practices.
This theoretical course covers the structural biochemistry and digestion/absorption processes of carbohydrates, lipids, and proteins, alongside intermediary metabolic pathways (Glycolysis, TCA, Oxidative Phosphorylation, Gluconeogenesis, Pentose Phosphate Pathway, Urea Cycle) and their allosteric/hormonal regulations. It investigates cellular membrane dynamics; the synthesis/degradation of fatty acids, cholesterol, ketone bodies, eicosanoids, and porphyrins, as well as plasma proteins and coagulation biochemistry at the molecular level. The course theoretically analyzes oxidative stress and antioxidant systems; hormone classification and signal transduction mechanisms; calcium, phosphorus, and magnesium mineral homeostasis alongside bone formation/resorption markers.
| 1. | Students will be able to explain the structure, metabolism, and regulation of carbohydrates, including glycolysis, TCA cycle, and related pathways. |
| 2. | Students will demonstrate understanding of lipid biochemistry, including digestion, absorption, synthesis, oxidation, and regulatory mechanisms. |
| 3. | Students will describe protein digestion processes, amino acid biosynthesis and degradation, as well as the urea cycle and related metabolic pathways. |
| 4. | Students will analyze the biochemical basis of blood coagulation, plasma proteins, connective tissue components, and extracellular matrix functions |
| 5. | Students will understand hormone classification, signal transduction mechanisms, and the metabolic regulation of calcium, phosphorus, magnesium, and bone remodeling markers. |
| 1. | Harper's Illustrated Bıochemıstry 32. Baskı |
| 2. | Lippincott’s Illustrated Reviews:Biochemistry Fifth Edition |
| 3. | Lehninger Principles Of Biochemistry by David L.-Nelson Michael M.Cox |
| 4. | Marks Clinical Fundamentals of Medical Biochemistry 2nd Edition |
| Type of Assessment | Count | Percent |
|---|---|---|
| Attending Lectures | 1 | %5 |
| Quiz | 1 | %5 |
| Midterm Examination | 2 | %30 |
| Final Examination | 1 | %60 |
| Activities | Count | Preparation | Time | Total Work Load (hours) |
|---|---|---|---|---|
| Lecture - Theory | 28 | 0 | 2 | 56 |
| Quiz | 1 | 2 | 1 | 3 |
| Midterm Examination | 1 | 5 | 1 | 6 |
| Final Examination | 1 | 9 | 1 | 10 |
| TOTAL WORKLOAD (hours) | 75 | |||
PÇ-1 | PÇ-2 | PÇ-3 | PÇ-4 | PÇ-5 | PÇ-6 | PÇ-7 | PÇ-8 | PÇ-9 | PÇ-10 | PÇ-11 | PÇ-12 | PÇ-13 | PÇ-14 | PÇ-15 | |
OÇ-1 | 5 | 4 | 1 | 3 | 2 | 3 | 2 | 1 | 3 | 2 | |||||
OÇ-2 | 5 | 4 | 1 | 3 | 2 | 3 | 2 | 1 | 3 | 2 | |||||
OÇ-3 | 5 | 5 | 1 | 3 | 2 | 4 | 2 | 1 | 3 | 3 | |||||
OÇ-4 | 5 | 5 | 2 | 3 | 3 | 4 | 3 | 1 | 3 | 1 | 2 | 3 | 1 | 1 | 4 |
OÇ-5 | 5 | 5 | 2 | 4 | 3 | 5 | 3 | 1 | 2 | 1 | 2 | 4 | 1 | 1 | 5 |