Information Package / Course Catalogue
Biophysics of Circulatory and Respiratory Systems
Course Code: BYF601
Course Type: Required
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 2
Credit: 3
Lab: 0
ECTS: 5
Objectives of the Course

The course aims to examine basic principles of hemodynamics, structure and function of circulation and respiration systems, physical properties of blood and viscosity, Poiseuille's law, Bernouilli's law, laminar and turbulent flow, Laplace's law, pressure, volume and resistance relations in blood vessels and respiratory system will be examined. Efficiency and power of heart, cardiac cycle, arterial pressure pulse proliferation and blood pressure measurement, gas laws related with respiration, surface tension and alveolar mechanics, compliance, respiration parameters.

Course Content

Basic principles of hemodynamics, structure and function of circulation and respiration systems, physical properties of blood and viscosity, Poiseuille's law, Bernouilli's law, laminar and turbulent flow, Laplace's law, pressure, volume and resistance relations in blood vessels and respiratory system will be examined. Efficiency and power of heart, cardiac cycle, arterial pressure pulse proliferation and blood pressure measurement, gas laws related with respiration, surface tension and alveolar mechanics, compliance, respiration parameters will be examined.

Name of Lecturer(s)
Learning Outcomes
1.Learn about concepts of hemodynamics
2.Gain knowlegde on the the structure and function of circulatory and respiratory systems and about the physical laws affective on circulatory and respiratory systems
3.Learn about the pressure, volume and resistance relationships of the vessels and respiratory system
4.Learn the techniques to measure blood pressure and blood flow theoritically and practically, learn about the biophysical aspects of the power, strength of the heart and cardiac cycle
5.Learn about the techniques to measure the volume and capacity of the lung, learn how to use and analyse spirometry
Recommended or Required Reading
1.Gürbüz Çelebi, Medical Physics, Barış Yayınları, Fakülte Kitabevi, İzmir 2010.
2.Ferit Pehlivan, Biophysics, Hacettepe-Taş Yayınevi, Ankara, 2011
3.Berne, Levy, Koeppen and Stanton, Physiology, Translation: Turkish Physiology Society, 2008.
4.Guyton and Hall, Medical Physiology, 2010
5.Şefik Dursun (ed.), Biophysics Lecture Notes, Cerrahpaşa Tıp Fak. Yayınevi, İstanbul, 2010
6.Russel K Hobbie, Intermediate physics form medicine and Biology,Springer-verlag, NY, 1997
Weekly Detailed Course Contents
Week 1 - Theoretical
Basic principles of hemodynamics
Week 1 - Practice
Hemodynamic parameter
Week 2 - Theoretical
Structure and function of the circulatory system, physical properties of blood and viscosity
Week 3 - Theoretical
Continuity equation, Bernouilli and Poiseuille laws, laminar and turbulent flow, reynould and march number
Week 3 - Practice
Red blood cell and white blood cell count, hematocrit measurement
Week 4 - Theoretical
Surface tension, Laplace law, pressure, volume and resistance relationships of the vessels
Week 4 - Practice
Blood flow and measurement of blood pressure
Week 5 - Theoretical
Surface tension, Laplace law, pressure, volume and resistance relationships of the vessels
Week 5 - Practice
Pressure and volume relationships in the heart
Week 6 - Theoretical
The strength and power of the heart, cardiac cycle, propagation of the arterial pressure pulse
Week 6 - Practice
ECG and its evaluation
Week 7 - Intermediate Exam
MIDTERM EXAMINATION
Week 8 - Theoretical
Structure and function of the respiratory system
Week 8 - Practice
Parameters of respiration
Week 9 - Theoretical
Gaseous laws related with respiration
Week 9 - Practice
Spirometric measurements
Week 10 - Theoretical
Surface tension and alveolar mechanics
Week 10 - Practice
Evaluation of spirometry
Week 11 - Theoretical
Lung and chest compliance
Week 11 - Practice
Measurement of blood gases
Week 12 - Theoretical
Pressure, volume and resistance alterations during respiration, the work of respiration
Week 12 - Practice
Pressure and volume alterations during respiration
Week 13 - Theoretical
Lung volume and capacities, spirometric measurements
Week 13 - Practice
Measurement of the EDA effect of respiration
Week 14 - Theoretical
Measurements of functional residual capacities
Week 14 - Practice
Measurements of functional residual capacities
Week 15 - Final Exam
Final Exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Presentation1%2.5
Assignment1%2.5
Midterm Examination1%25
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory131239
Lecture - Practice131239
Assignment18210
Presentation 1516
Midterm Examination110212
Final Examination112214
TOTAL WORKLOAD (hours)120
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
PÇ-14
PÇ-15
PÇ-16
PÇ-17
PÇ-18
PÇ-19
PÇ-20
OÇ-1
5
5
4
5
4
1
1
1
1
1
1
1
1
5
2
1
1
1
4
1
OÇ-2
5
5
5
5
4
1
2
1
2
2
1
1
1
5
3
2
1
1
4
1
OÇ-3
5
5
4
5
4
1
1
3
1
1
1
1
1
5
3
1
1
1
4
2
OÇ-4
5
5
4
5
4
1
1
2
1
1
1
1
1
5
2
1
1
1
4
1
OÇ-5
5
5
4
5
4
1
1
1
1
1
1
1
1
5
2
1
2
1
4
4
Adnan Menderes University - Information Package / Course Catalogue
2026