Information Package / Course Catalogue
Membrane Biophsysics
Course Code: BYF604
Course Type: Required
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 0
Credit: 2
Lab: 0
ECTS: 4
Objectives of the Course

The course aims to introduce cell membrane structure, cell membrane receptors, permeability properties of cell membrane, structure and function of ion channels and electrical equivalent circuit of cell membrane.

Course Content

Cell membrane structure, cell membrane receptors, permeability properties of cell membrane, structure and function of ion channels and electrical equivalent circuit of cell membrane.

Name of Lecturer(s)
Learning Outcomes
1.Gaining knowledge on the structure of membranes and the functions of the components of membranes
2.Learning the role of membrane receptors in signal transduction and the transport in membranes
3.Gaining knowledge on the structure, function and types of ion channels in membranes
4.Learning about passive and electrical properties of membranes and electrical circuit of the membrane
5.To comprehend the active membrane properties and the events during the generation and conductance of action potential
Recommended or Required Reading
1.Nuhan Puralı, Cellular electrophysiology and principles of visualization, Veri Medikal, Ankara, 2008
2.Gürbüz Çelebi, Medical Physics, Barış yayınları fakülte kitabevi, İzmir, 2008
3.Ferit Pehlivan, Biophysics, Hacettepe-Taş yayınevi, Ankara, 2005
4.Nelson and Fox, Lehninger principles of biochemistry, 5th edition, 2011.
5.Guyton and Hall, Medical Physiology, 2010
6.Şefik Dursun (ed.) Biophysics lecture Notes, Cerrahpaşa Tıp Fak. Yayınevi, İstanbul, 2010
7.E.R.Kandel et al (eds), Principles of Neural Sciences, 2000.
8.Lodish&Baltimore et al (eds.), Moleculer Cell Biology, 2004.
9.GG Matthews (ed.), Neurobiology 2000
10.J.E. Blankenship (ed.), Neurophysiology, 2003.
Weekly Detailed Course Contents
Week 1 - Theoretical
Membrane structure, lipids, proteins and lipid rafts
Week 2 - Theoretical
Membrane fluidity, movement of lipids and proteins
Week 3 - Theoretical
Methods for measurement of membrane fluidity, green fluorescence protein, FRAP
Week 4 - Theoretical
Structure and function of membrane proteins
Week 5 - Theoretical
Membrane protein functions (transport, receptors, connection, enzyme)
Week 6 - Theoretical
Membrane transport, osmosis, diffusion, facilitated diffusion, co-transporter, endocytosis, exocytosis, active transport
Week 7 - Intermediate Exam
Midterm exam
Week 8 - Theoretical
Ion channels and their functions in membranes of exciatable cells
Week 9 - Theoretical
Electrical properties of cell membrane, membrane potential
Week 10 - Theoretical
Propagation in membranes: Graded potential and action potential
Week 11 - Theoretical
Electrical circuit of cell membrane, pssive membrane model and cable teory
Week 12 - Theoretical
Membrane receptors and their role in signal transduction
Week 13 - Theoretical
Membrane receptors: G-proteins and their relation with cholera
Week 14 - Theoretical
Signal transduction in membranes
Week 15 - Final Exam
Final exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Presentation1%2.5
Assignment1%2.5
Midterm Examination1%25
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory131239
Assignment110111
Presentation 1819
Midterm Examination114216
Final Examination118220
TOTAL WORKLOAD (hours)95
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
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PÇ-12
PÇ-13
PÇ-14
PÇ-15
PÇ-16
PÇ-17
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PÇ-19
PÇ-20
OÇ-1
5
2
4
2
4
3
1
5
4
2
1
1
5
1
3
2
2
2
5
1
OÇ-2
5
3
5
3
4
1
1
3
5
4
1
1
5
1
3
1
1
1
5
2
OÇ-3
5
3
5
3
5
2
1
4
5
4
1
1
5
1
4
1
1
1
5
2
OÇ-4
5
3
5
3
4
1
4
2
5
4
1
1
5
1
3
1
1
1
5
1
OÇ-5
5
4
5
3
4
1
2
3
5
4
1
1
5
1
3
1
1
1
5
3
Adnan Menderes University - Information Package / Course Catalogue
2026