Information Package / Course Catalogue
Neuroendocrinology and Neuroimmunology
Course Code: BYF648
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 3
Prt.: 0
Credit: 3
Lab: 0
ECTS: 5
Objectives of the Course

The course aims to investigate the central and peripheral nervous systems, related endocrine glands and how hormones function in the brain to regulate physiology and behavior.

Course Content

The course will investigate central and peripheral nervous system and related endocrine glands, how hormones function in the brain to regulate physiology and behavior. Particular emphasis is placed on neuropeptides and also more details on the organization and operation of different hypothalamus-pituitary-endocrine gland axes will be presented. In addition, the in vitro, in vivo and in situ properties of neuroimmune system elements and related functional disorders will be presented.

Name of Lecturer(s)
Learning Outcomes
1.To learn the secretory glands related to nervous system, the roles of brain hormones in regulation of physiology and behavior
2.To learn about neuropeptides and the organization and functioning of hypothalamus-pituatary-endocrine gland axis
3.To learn the nervous system diseases related to regulatory and control systems and their action mechanisms
4.To learn the components of neuroimmune system and the regulation of immune response by the nervous system
5.To gain knowledge on the interaction of neuroendocrine and immune system and the neuroimmune pathologies
Recommended or Required Reading
1.E.R.Kandel et al (eds), Principles of Neural Sciences, 2000
2.J.E. Blankenship (ed.), Neurophysiology, 2003.
3.Neumann H.Molecular mechanisms of axonal damage in inflammatory central nervous system diseases. Curr Opin Neurol. 2003 Jun;16 (3):267-73
Weekly Detailed Course Contents
Week 1 - Theoretical
The organization of neuroendocrine system, anatomy of hypothalamus, pituatary gland and cellar area
Week 2 - Theoretical
Physiology and hormonal regulation of hypothalamic-pituatary axis: Neurohypophysis, vasopressin, oxcytocin, TRH, CRH, GHRH
Week 3 - Theoretical
Physiology and hormonal regulation of hypothalamic-pituatary axis: somatostatin, prolactin, regulatory factors, LHRH, melanocortin
Week 4 - Theoretical
Neuroendocrine control of hypophysis hormones
Week 5 - Theoretical
Disorders of neuroendocrine system and diseases
Week 6 - Theoretical
Disorders of neuroendocrine system and diseases
Week 7 - Theoretical
Principles of autoimmunity, basic mechanisms in neuroimmunology
Week 8 - Intermediate Exam
Midterm exam
Week 9 - Theoretical
Molecular mechanisms in neuroimmunology and second messanger systems
Week 10 - Theoretical
Interferons and immunoglobulins: action mechanisms and indications
Week 11 - Theoretical
Blood-brain barrier
Week 12 - Theoretical
Neurogenic inflammation and demyelinization
Week 13 - Theoretical
Immune-mediated nervous system disorders
Week 14 - Theoretical
The relation in between neuroendocrinology and neuroimmunology
Week 15 - Final Exam
Final exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Presentation1%2.5
Assignment1%2.5
Midterm Examination1%25
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory132365
Assignment116218
Presentation 110212
Midterm Examination112315
Final Examination116319
TOTAL WORKLOAD (hours)129
Contribution of Learning Outcomes to Programme Outcomes
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OÇ-1
5
5
5
4
5
3
3
5
4
4
3
4
4
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4
3
3
3
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4
OÇ-2
5
5
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5
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4
4
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4
4
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3
3
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4
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5
5
5
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5
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4
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4
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3
3
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5
5
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5
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4
4
3
4
4
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4
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3
3
4
4
OÇ-5
5
5
5
4
5
2
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4
4
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4
4
2
4
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3
3
4
5
Adnan Menderes University - Information Package / Course Catalogue
2026