
| Course Code | : BDB228 |
| Course Type | : Required |
| Couse Group | : First Cycle (Bachelor's Degree) |
| Education Language | : Turkish |
| Work Placement | : N/A |
| Theory | : 2 |
| Prt. | : 0 |
| Credit | : 2 |
| Lab | : 0 |
| ECTS | : 4 |
The objective of this course is to provide Nutrition and Dietetics students with the fundamental mechanisms of molecular biology and genetics (central dogma, gene expression, mutations). The course aims to facilitate comprehension of the interactions between nutrients and the genetic blueprint through nutrigenetics, nutrigenomics, and epigenetics, and to enable the molecular evaluation of contemporary topics like cancer biology and GMOs within the framework of nutritional science.
This course covers the molecular structure of the cell, macromolecules, nucleic acid organization, and information flow processes (replication, transcription, translation). Investigating gene expression regulation, mutations, and variations, the course focuses on the concepts of nutrigenetics, nutrigenomics, and epigenetics, which address the impacts of nutrition on the genetic blueprint. Additionally, cell cycle regulation, apoptosis, the molecular basis of cancer, and contemporary biotechnological advancements such as GMOs are discussed within the axis of nutritional science.
| 1. | Explains the molecular structure of the cell, the characteristics of biological macromolecules, and the genomic organization of nucleic acids (DNA/RNA). |
| 2. | Comprehends the DNA replication, transcription, and translation mechanisms, as well as the post-transcriptional/post-translational modifications and repair systems involved in these processes. |
| 3. | Distinguishes the regulation mechanisms of gene expression, and the impacts of genetic mutations, polymorphisms, and variations on cellular functions and individual differences. |
| 4. | Explains the core principles of nutrigenetics and nutrigenomics, relating the roles of nutrients in gene expression and epigenetic mechanisms to professional practice. |
| 5. | Defines cell cycle regulation, apoptosis, and the molecular biology of cancer; and evaluates the contemporary implications of biotechnological advancements such as recombinant DNA technology and GMOs in the field of nutrition. |
| 1. | Karataş M, editor. Hücre Biyolojisi. Ankara: Nobel Akademik Yayıncılık; 2022. |
| 2. | Yüce S, Bilgen G, vd. Genetik. Ankara: Nobel Akademik Yayıncılık, 2024. |
| 3. | Lodish H., Berk A., Kaiser C.A. ve ark. Molecular Cell Biology,2007 |
| 4. | Chandar N, Viselli S. Lippincott Hücre ve Moleküler Biyoloji. 3. Baskı. Çev. Ed. Yanık Sarıbaş B. İstanbul: Nobel Tıp Kitabevi; 2025. |
| Type of Assessment | Count | Percent |
|---|---|---|
| Attending Lectures | 1 | %5 |
| Quiz | 1 | %5 |
| Midterm Examination | 1 | %30 |
| Final Examination | 1 | %60 |
| Activities | Count | Preparation | Time | Total Work Load (hours) |
|---|---|---|---|---|
| Lecture - Theory | 14 | 3 | 2 | 70 |
| Quiz | 1 | 2 | 1 | 3 |
| Midterm Examination | 1 | 12 | 1 | 13 |
| Final Examination | 1 | 15 | 1 | 16 |
| TOTAL WORKLOAD (hours) | 102 | |||
PÇ-1 | PÇ-2 | PÇ-3 | PÇ-4 | PÇ-5 | PÇ-6 | PÇ-7 | PÇ-8 | PÇ-9 | PÇ-10 | |
OÇ-1 | 3 | 2 | ||||||||
OÇ-2 | 3 | 2 | ||||||||
OÇ-3 | 3 | 1 | 2 | 1 | ||||||
OÇ-4 | 3 | 3 | 2 | 3 | 2 | 2 | ||||
OÇ-5 | 3 | 2 | 2 | 2 | 2 | 3 | 1 | 2 | ||