Information Package / Course Catalogue
Nutrigenomics
Course Code: BDB323
Course Type: Area Elective
Couse Group: First Cycle (Bachelor's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 0
Credit: 2
Lab: 0
ECTS: 4
Objectives of the Course

The objective of this course is to provide students with the interaction between genetic variations and nutrition at the molecular level. Within the scope of the course, by examining the roles of polymorphisms (SNPs), gene expression, and epigenetic mechanisms in chronic diseases (obesity, cancer, diabetes), it is aimed for students to gain the ability to plan individualized medical nutrition therapies and develop ethical approaches tailored to the genetic background.

Course Content

This course covers the concepts of nutrigenetics and nutrigenomics, gene-environment interactions, and single nucleotide polymorphisms (SNPs). It addresses the pathogenesis of chronic diseases, plasma lipid profiles, the regulatory mechanisms of fatty acids and micronutrients on gene expression, and the safety of bioactive food components. Additionally, nutrigenetic approaches in pathologies such as metabolic syndrome, insulin resistance, cardiovascular diseases, and cancer; the effects of genetics on appetite, eating behavior, and obesity; and epigenetic and ethical dimensions in nutrition are investigated.

Name of Lecturer(s)
Learning Outcomes
1.Explains the concepts of nutrigenetics, nutrigenomics, and single nucleotide polymorphisms (SNPs), interpreting the dynamic role of gene-environment interactions on chronic disease pathogenesis and plasma lipid profiles using evidence-based data.
2.Analyzes the effects of nutrients and bioactive components on gene expression, evaluating the roles of polyunsaturated fatty acids in gene regulation regarding safety and efficacy.
3.Defines individual nutritional requirements based on genetic variations, distinguishing gene-nutrient interaction mechanisms in metabolic syndrome, insulin resistance, and cardiovascular diseases.
4.Explains the role of nutrition in the molecular epidemiology of cancer, relating the effects of genetic variations on individuals' eating behavior, appetite control, vitamin metabolism, and obesity pathology.
5.Defines epigenetic mechanisms and future molecular approaches in nutrition, evaluating professional ethical boundaries and legal dimensions in nutrigenetic testing and personalized nutrition practices.
Recommended or Required Reading
1.A.P.Simopoulos, J.M. Ordovas, Nutrigenetics and Nutrigenomics, Karger
2.Baş, M., & Karaca Çelik, K.E. (Çev. Ed.). (2023). Nutrigenetik: Kişisel Beslenme Bilimini Uygulamak. Ankara: Akademisyen Kitabevi. ISBN: 978-625-399-006-0.
Weekly Detailed Course Contents
Week 1 - Theoretical
Concepts of Nutrigenetics and Nutrigenomics: Genetic Variations and Nutrition
Week 2 - Theoretical
Gene-Environment Interaction and Single Nucleotide Polymorphisms (SNPs)
Week 3 - Theoretical
Pathogenesis of Chronic Diseases: Dynamic Relationship Between Genome and Environmental Factors
Week 4 - Theoretical
Genes, Diet, and Plasma Lipid Profile: Epidemiological and Observational Evidence
Week 5 - Theoretical
Nutrients and Gene Expression: Transcriptional Regulation
Week 6 - Theoretical
Safety and Efficacy Evaluation in Nutrigenomics: Bioactive Food Components
Week 7 - Theoretical
Polyunsaturated Fatty Acids (Omega-6 / Omega-3 Ratio) and Gene Regulation
Week 8 - Theoretical
Individual Nutritional Requirements Based on Genetic Variations / Midterm exam
Week 9 - Theoretical
Metabolic Syndrome: Gene-Nutrient Interaction and Insulin Resistance Mechanisms / Assessment of Midterm Examination Questions
Week 10 - Theoretical
Cardiovascular Diseases and Nutrigenetic Approaches
Week 11 - Theoretical
Molecular Epidemiology of Cancer and Nutrigenomics
Week 12 - Theoretical
Vitamin Metabolism: Micronutrients, Genetic Variations, and Environment Interaction
Week 13 - Theoretical
Effects of Genetic Variations on Eating Behavior, Appetite Regulation, and Obesity
Week 14 - Theoretical
Epigenetic Mechanisms and Nutrition: Future Approaches and Ethical Dimensions
Assessment Methods and Criteria
Type of AssessmentCountPercent
Attending Lectures1%5
Quiz1%5
Midterm Examination1%30
Final Examination1%60
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory134278
Quiz1213
Midterm Examination110111
Final Examination110111
TOTAL WORKLOAD (hours)103
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
OÇ-1
5
3
3
2
OÇ-2
4
2
1
OÇ-3
4
5
2
5
3
OÇ-4
4
4
2
5
3
OÇ-5
4
3
3
2
5
2
4
Adnan Menderes University - Information Package / Course Catalogue
2026