
| Course Code | : BDB323 |
| Course Type | : Area Elective |
| Couse Group | : First Cycle (Bachelor's Degree) |
| Education Language | : Turkish |
| Work Placement | : N/A |
| Theory | : 2 |
| Prt. | : 0 |
| Credit | : 2 |
| Lab | : 0 |
| ECTS | : 4 |
The objective of this course is to provide students with the interaction between genetic variations and nutrition at the molecular level. Within the scope of the course, by examining the roles of polymorphisms (SNPs), gene expression, and epigenetic mechanisms in chronic diseases (obesity, cancer, diabetes), it is aimed for students to gain the ability to plan individualized medical nutrition therapies and develop ethical approaches tailored to the genetic background.
This course covers the concepts of nutrigenetics and nutrigenomics, gene-environment interactions, and single nucleotide polymorphisms (SNPs). It addresses the pathogenesis of chronic diseases, plasma lipid profiles, the regulatory mechanisms of fatty acids and micronutrients on gene expression, and the safety of bioactive food components. Additionally, nutrigenetic approaches in pathologies such as metabolic syndrome, insulin resistance, cardiovascular diseases, and cancer; the effects of genetics on appetite, eating behavior, and obesity; and epigenetic and ethical dimensions in nutrition are investigated.
| 1. | Explains the concepts of nutrigenetics, nutrigenomics, and single nucleotide polymorphisms (SNPs), interpreting the dynamic role of gene-environment interactions on chronic disease pathogenesis and plasma lipid profiles using evidence-based data. |
| 2. | Analyzes the effects of nutrients and bioactive components on gene expression, evaluating the roles of polyunsaturated fatty acids in gene regulation regarding safety and efficacy. |
| 3. | Defines individual nutritional requirements based on genetic variations, distinguishing gene-nutrient interaction mechanisms in metabolic syndrome, insulin resistance, and cardiovascular diseases. |
| 4. | Explains the role of nutrition in the molecular epidemiology of cancer, relating the effects of genetic variations on individuals' eating behavior, appetite control, vitamin metabolism, and obesity pathology. |
| 5. | Defines epigenetic mechanisms and future molecular approaches in nutrition, evaluating professional ethical boundaries and legal dimensions in nutrigenetic testing and personalized nutrition practices. |
| 1. | A.P.Simopoulos, J.M. Ordovas, Nutrigenetics and Nutrigenomics, Karger |
| 2. | Baş, M., & Karaca Çelik, K.E. (Çev. Ed.). (2023). Nutrigenetik: Kişisel Beslenme Bilimini Uygulamak. Ankara: Akademisyen Kitabevi. ISBN: 978-625-399-006-0. |
| Type of Assessment | Count | Percent |
|---|---|---|
| Attending Lectures | 1 | %5 |
| Quiz | 1 | %5 |
| Midterm Examination | 1 | %30 |
| Final Examination | 1 | %60 |
| Activities | Count | Preparation | Time | Total Work Load (hours) |
|---|---|---|---|---|
| Lecture - Theory | 13 | 4 | 2 | 78 |
| Quiz | 1 | 2 | 1 | 3 |
| Midterm Examination | 1 | 10 | 1 | 11 |
| Final Examination | 1 | 10 | 1 | 11 |
| TOTAL WORKLOAD (hours) | 103 | |||
PÇ-1 | PÇ-2 | PÇ-3 | PÇ-4 | PÇ-5 | PÇ-6 | PÇ-7 | PÇ-8 | PÇ-9 | PÇ-10 | |
OÇ-1 | 5 | 3 | 3 | 2 | ||||||
OÇ-2 | 4 | 2 | 1 | |||||||
OÇ-3 | 4 | 5 | 2 | 5 | 3 | |||||
OÇ-4 | 4 | 4 | 2 | 5 | 3 | |||||
OÇ-5 | 4 | 3 | 3 | 2 | 5 | 2 | 4 | |||