Information Package / Course Catalogue
The Molecular Basis of Mutation
Course Code: BİO502
Course Type: Area Elective
Couse Group: Second Cycle (Master's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 3
Prt.: 0
Credit: 3
Lab: 0
ECTS: 6
Objectives of the Course

Detailed information about the molecular basis of the concept of mutation and mutations

Course Content

Information about the molecular basis of the concept of mutation and mutations

Name of Lecturer(s)
Learning Outcomes
1.To be able to gain knowledge about the basic information of mutation
2.To be able to understand the importance of mutation for life
3.To be able to acquire gene mutations
4.To be able to learn the Structural chromosomal mutations
5.To be able to gain information on mutation analyzing in mammals
Recommended or Required Reading
1.J.W.Drake (1970). The molecular basis of mutation, Holden-day Inc.
2.E.C. Friedberg, G.C. Walker, W.Siede ( 1995). DNA repair and Mutagenesis, ASM Press
Weekly Detailed Course Contents
Week 1 - Theoretical
Introduction to mutations, mutant, mutagen concepts
Week 2 - Theoretical
The mechanism of occurrence of mutation, the origin of mutations.
Week 3 - Theoretical
Direction of mutations, mutation rates.
Week 4 - Theoretical
Classification of mutagens (Chemical mutagens)
Week 5 - Theoretical
Classification of mutagens (physical mutagens)
Week 6 - Theoretical
Classification of mutations
Week 7 - Theoretical
Spontan mutarions
Week 8 - Theoretical
Structural Chromosome mutations (Midterm exam)
Week 9 - Theoretical
Numerical Chromosome mutations
Week 10 - Theoretical
Gene mutations
Week 11 - Theoretical
Mutagenesis in prokaryotes
Week 12 - Theoretical
mutagenesis in eukaryotes and DNA damage repair systems
Week 13 - Theoretical
Molecular methods used to identify and analyze mutations
Week 14 - Theoretical
Mutation analysis in mammalian cells
Assessment Methods and Criteria
Type of AssessmentCountPercent
Attending Lectures1%5
Verbal Examination1%5
Midterm Examination1%20
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory142370
Assignment82016
Term Project115015
Reading141014
Midterm Examination115217
Final Examination115217
TOTAL WORKLOAD (hours)149
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
OÇ-1
4
4
4
4
4
OÇ-2
4
4
4
3
4
OÇ-3
4
3
3
3
3
OÇ-4
4
4
4
3
OÇ-5
4
3
4
3
4
Adnan Menderes University - Information Package / Course Catalogue
2026