Information Package / Course Catalogue
Cell Cycle and Regulation
Course Code: BİO563
Course Type: Area Elective
Couse Group: Second Cycle (Master's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 0
Credit: 2
Lab: 0
ECTS: 6
Objectives of the Course

The aim of this introduction of Cell Cycle and Regulation is to identify the cell cycle with the mechanisms that control the cell cycle, explain the conservation of the cell cycle in evolutional process and exert the relation with cancer.

Course Content

In content of this course cell cycle, genetic regulation and checkpoints, proteins which taking part in this points and their interactions, relation of intracellular components with the cycle, cell cycle arrest, lose of control and cancer topics will be discussed.

Name of Lecturer(s)
Learning Outcomes
1.To be able to comprehend the cell cycle and checkpoints
2.To be able to explain cell cycle progression in checkpoints and interactions between attendant components
3.To be able to discuss functions of cyclins, cdk's and its inhibitors over literature
4.To be able to associate extracellular and intracellular factors with cell cycle
5.To be able to explain the importance of cell cycle regulation and its relation with cancer
Recommended or Required Reading
1.The Cell Cycle: Principles of Control, David O. Morgan, 2007, Oxford University Pres.
2.Molecular Biology of the Cell, Bruce Alberts ve Alexnader Johnson 2008, Ankara-TÜBA
Weekly Detailed Course Contents
Week 1 - Theoretical
Cell cycle
Week 2 - Theoretical
Genetic control of the cell cycle in yeast
Week 3 - Theoretical
Cell cycle checkpoints
Week 4 - Theoretical
Checkpoints, genes and proteins
Week 5 - Theoretical
Cyclins and cyclin dependent kinases
Week 6 - Theoretical
Regulation of G1, S, G2 and M phase progressions
Week 7 - Theoretical
Chromosomal replication and cyclins
Week 8 - Intermediate Exam
Midterm Exam
Week 9 - Theoretical
Assembling of mitotic spindles and control of chromosomal segregation
Week 10 - Theoretical
Cyclin-dependent kinase inhibitors and cell cycle disruption
Week 11 - Theoretical
Relationship between the cellular skeleton and the cell cycle
Week 12 - Theoretical
Extracellular molecules and receptors
Week 13 - Theoretical
Escape of cell cycle from control
Week 14 - Theoretical
Carcinogenesis and cell cycle
Week 15 - Theoretical
Literature search
Assessment Methods and Criteria
Type of AssessmentCountPercent
Attending Lectures1%2
Verbal Examination1%3
Midterm Examination1%25
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory145298
Midterm Examination120424
Final Examination130434
TOTAL WORKLOAD (hours)156
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
OÇ-1
5
4
4
OÇ-2
5
5
4
OÇ-3
5
5
4
4
4
5
OÇ-4
5
5
4
4
OÇ-5
5
4
4
4
4
4
Adnan Menderes University - Information Package / Course Catalogue
2026