Information Package / Course Catalogue
| Course Code | : BİO575 |
| Course Type | : Area Elective |
| Couse Group | : Second Cycle (Master's Degree) |
| Education Language | : Turkish |
| Work Placement | : N/A |
| Theory | : 3 |
| Prt. | : 0 |
| Credit | : 3 |
| Lab | : 0 |
| ECTS | : 6 |
The aim of this course is to give information about the classical and modern techniques related to chromosome structure, function, and organization.
Investigation of chromosome number, structure, function and gene inheritance, organization and expression is an integral part of the cytogenetic science. The continuity of inherited traits separating the basic groups of living organisms depends on the integrity of the chromosomes and genes. Chromosomes and related DNA molecules are reproduced in an exceptionally accurate manner through infinite cell and organism belts. Therefore, for a given organism type, the same chromosome number and structure should be understood in different cells of the same organ or tissue, whether in the same species or in a single individual.
| 1. | Knows the history of chromosome biology. |
| 2. | Describe the structure, tasks and molecular organization of human genome |
| 3. | Explain chromosome concentration (nucleosomes) and chromosome |
| 4. | Learns the role of chromosomes in cell division |
| 5. | Explain mitotic and meiotic chromosome structure and karyotype |
| 6. | Knows the mechanisms of centromere, telomer and aging |
| 7. | Structural Chromosome anomalies - Define the loss or gain of chromosome fragments |
| 8. | Learns the relationship between numerical chromosomal anomalies and genetic diseases |
| 9. | Knows DNA and chromosomes in organelles |
| 10. | Learn new chromosome analysis techniques |
| 11. | Learns chromosome banding methods |
| 12. | Explain the methods of chromosome staining by GISH and FISH method |
| 13. | Learn how artificial chromosomes are formed |
| 14. | Define the toxicity tests based on chromosomes. |
| 1. | Chromosomes, Miller, F.P., Vandome, A.F., Mcbrewster.J.. Alphascript Publishing, 2009 |
| 2. | Chromosome Techniques: Theory and Practice. Sharma, A.K. and Sharma, A. Butterworths, London, 1980 |
| 3. | Chromosome Biology, Apples,R., Morris,R., Gill.S.B., May, CE., Springer,1998 |
| Type of Assessment | Count | Percent |
|---|---|---|
| Attending Lectures | 1 | %5 |
| Assignment | 2 | %10 |
| Midterm Examination | 1 | %15 |
| Final Examination | 1 | %70 |
| Activities | Count | Preparation | Time | Total Work Load (hours) |
|---|---|---|---|---|
| Lecture - Theory | 14 | 1 | 3 | 56 |
| Assignment | 2 | 5 | 5 | 20 |
| Term Project | 4 | 0 | 3 | 12 |
| Individual Work | 10 | 0 | 2 | 20 |
| Quiz | 1 | 1 | 1 | 2 |
| Midterm Examination | 1 | 18 | 1 | 19 |
| Final Examination | 1 | 20 | 1 | 21 |
| TOTAL WORKLOAD (hours) | 150 | |||
PÇ-1 | PÇ-2 | PÇ-3 | PÇ-4 | PÇ-5 | PÇ-6 | PÇ-7 | PÇ-8 | PÇ-9 | PÇ-10 | PÇ-11 | PÇ-12 | |
OÇ-1 | 4 | |||||||||||
OÇ-2 | 1 | |||||||||||
OÇ-3 | 2 | |||||||||||
OÇ-4 | 2 | |||||||||||
OÇ-5 | 2 | |||||||||||
OÇ-6 | 4 | |||||||||||
OÇ-7 | 1 | |||||||||||
OÇ-8 | 3 | |||||||||||
OÇ-9 | 1 | |||||||||||
OÇ-10 | 2 | |||||||||||
OÇ-11 | 2 | |||||||||||
OÇ-12 | 3 | |||||||||||
OÇ-13 | 2 | |||||||||||
OÇ-14 | 5 | |||||||||||