Information Package / Course Catalogue
Intestinal Friendly Molecules: Probiotics, Paraprobiotics and Postbiotics
Course Code: ST322
Course Type: Area Elective
Couse Group: First Cycle (Bachelor's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 0
Credit: 2
Lab: 0
ECTS: 2
Objectives of the Course

The aim of this course is to understand the relationship between the gut microbiota and human health, and to teach the concepts of probiotics, paraprobiotics, and postbiotics along with their scientific foundations. Students will gain detailed knowledge about the production processes, mechanisms of action, health effects, and applications of these molecules in functional foods, reaching a level where they can analyze current literature in the field.

Course Content

This course focuses on the gut microbiota, which plays a critical role in human health, and the related biological molecules. The course covers in detail the definition, sources, health effects, and industrial applications of probiotics, while also providing a comprehensive overview of the increasingly important concepts of paraprobiotics and postbiotics. Inactivation methods used in the production of paraprobiotics and the effects of their cellular components, as well as the metabolites contained in postbiotics and their mechanisms of action, will be evaluated comparatively. Students will learn about the interactions of these molecules with the microbiota, their roles in the immune system, and their potential therapeutic applications; additionally, they will have the opportunity to develop critical analysis and presentation skills based on current scientific literature.

Name of Lecturer(s)
Learning Outcomes
1.Explains the structure, functions, and effects of the gut microbiota on human health.
2.Defines and distinguishes the concepts of probiotics, paraprobiotics, and postbiotics.
3.Describes the production methods, mechanisms of action, and potential health effects of these components.
4.Compares and evaluates the interactions of live and inactivated microorganisms with the microbiota.
5.Explains applications of probiotics, paraprobiotics, and postbiotics in food and health sectors with examples.
6.Analyzes current studies from scientific literature and interprets them with a critical perspective.
7.Develops knowledge on the use of microbial components in the development of functional foods and supplements.
8.Communicates research findings effectively in written and oral academic presentation formats.
Recommended or Required Reading
1.Handbook of Probiotics and Prebiotics (2008). Yuan Kun Lee, Seppo Salminen. John Wiley & Sons, Inc.
2.Postbiotics: Science, Technology and Applications (2021). Amin Abbasi, Elham Sheykhsaran, Hossein Samadi Kafil. Bentham Books
Weekly Detailed Course Contents
Week 1 - Theoretical
Introduction and Basic Concepts
Week 2 - Theoretical
Structure and Functions of the Gut Microbiota
Week 3 - Theoretical
Definition and History of Probiotics
Week 4 - Theoretical
Probiotic Microorganisms and Their Sources
Week 5 - Theoretical
Health Effects of Probiotics
Week 6 - Theoretical
Viability and Stability of Probiotics
Week 7 - Theoretical
Paraprobiotics: Definition and Conceptual
Week 8 - Theoretical
Production and Inactivation Methods of Paraprobiotics
Week 9 - Theoretical
Health Effects of Paraprobiotics
Week 10 - Theoretical
Postbiotics: Definition, Classification, and Mechanisms
Week 11 - Theoretical
Postbiotics: Definition, Classification, and Mechanisms
Week 12 - Theoretical
Production and Applications of Postbiotics
Week 13 - Theoretical
Comparison of Probiotics, Paraprobiotics, and Postbiotics
Week 14 - Theoretical
Current Research and Clinical Studies
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%40
Final Examination1%60
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory140228
Individual Work141014
Midterm Examination1415
Final Examination1415
TOTAL WORKLOAD (hours)52
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
OÇ-1
5
5
4
5
4
5
4
OÇ-2
5
5
4
5
4
5
4
OÇ-3
5
5
4
5
4
5
4
OÇ-4
5
5
4
5
4
5
4
OÇ-5
5
5
4
5
4
5
4
OÇ-6
5
5
4
5
4
5
4
OÇ-7
5
5
4
5
4
5
4
OÇ-8
5
5
4
5
4
5
4
Adnan Menderes University - Information Package / Course Catalogue
2026